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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D3B
All Species:
3.94
Human Site:
S246
Identified Species:
14.44
UniProt:
A6NDS4
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NDS4
NP_001001417.5
549
62315
S246
Q
E
H
V
V
A
T
S
Q
S
K
T
M
G
H
Chimpanzee
Pan troglodytes
XP_001173074
549
62288
S246
Q
E
H
E
V
A
T
S
Q
L
K
T
M
G
H
Rhesus Macaque
Macaca mulatta
XP_001112605
584
64806
A261
A
V
L
K
H
L
R
A
S
T
K
K
L
T
R
Dog
Lupus familis
XP_544260
839
96074
F262
H
E
K
I
L
N
K
F
L
S
K
L
K
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80XC3
819
93555
F245
H
E
K
I
L
N
K
F
L
S
K
L
K
Q
H
Rat
Rattus norvegicus
Q4QQU7
289
32911
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLZ0
342
39660
L52
R
A
L
K
W
S
K
L
L
Q
Q
S
A
A
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
55.9
23.9
N.A.
24.5
22.5
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
62.8
38.2
N.A.
37.6
32.4
N.A.
N.A.
N.A.
35.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
6.6
26.6
N.A.
26.6
0
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
26.6
40
N.A.
40
0
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
0
0
29
0
15
0
0
0
0
15
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
58
0
15
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% G
% His:
29
0
29
0
15
0
0
0
0
0
0
0
0
0
58
% H
% Ile:
0
0
0
29
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
29
29
0
0
43
0
0
0
72
15
29
0
0
% K
% Leu:
0
0
29
0
29
15
0
15
43
15
0
29
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% M
% Asn:
0
0
0
0
0
29
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
29
0
0
0
0
0
0
0
29
15
15
0
0
29
0
% Q
% Arg:
15
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% R
% Ser:
0
0
0
0
0
15
0
29
15
43
0
15
0
0
0
% S
% Thr:
0
0
0
0
0
0
29
0
0
15
0
29
0
15
0
% T
% Val:
0
15
0
15
29
0
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _